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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMPH All Species: 12.73
Human Site: S396 Identified Species: 31.11
UniProt: P49418 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49418 NP_001626.1 695 76257 S396 T D L V Q P A S G G S F N G F
Chimpanzee Pan troglodytes XP_519055 930 101395 D499 T D L V Q P T D S S E S L S L
Rhesus Macaque Macaca mulatta XP_001100126 694 76130 S396 A D L V Q P A S G G S F N G F
Dog Lupus familis XP_533085 836 91248 D415 T D L V Q P T D S S K S L S L
Cat Felis silvestris
Mouse Mus musculus Q7TQF7 686 74995 S396 T D L V Q P A S G G S F N D F
Rat Rattus norvegicus O08838 683 74859 Q393 T T S T D L V Q P A S G G S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516791 687 75140 S396 S E L V Q P A S S G A F N G F
Chicken Gallus gallus P50478 682 75187 L388 L W T T T S E L V Q P A S S T
Frog Xenopus laevis NP_001085079 666 74474 Q375 A A T V G I V Q S H S P I S Q
Zebra Danio Brachydanio rerio NP_957125 784 85747 A396 A T D A G F T A N W A A D F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 97.4 63 N.A. 85.1 86.4 N.A. 74.9 72 61.4 50.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73 98.2 68.6 N.A. 88 89 N.A. 82.3 80.5 71.6 64.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 93.3 40 N.A. 93.3 20 N.A. 73.3 0 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 93.3 40 N.A. 93.3 20 N.A. 93.3 6.6 13.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 0 10 0 0 40 10 0 10 20 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 10 0 10 0 0 20 0 0 0 0 10 10 0 % D
% Glu: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 40 0 10 50 % F
% Gly: 0 0 0 0 20 0 0 0 30 40 0 10 10 30 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 60 0 0 10 0 10 0 0 0 0 20 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 40 0 0 % N
% Pro: 0 0 0 0 0 60 0 0 10 0 10 10 0 0 0 % P
% Gln: 0 0 0 0 60 0 0 20 0 10 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 0 0 10 0 40 40 20 50 20 10 50 0 % S
% Thr: 50 20 20 20 10 0 30 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 70 0 0 20 0 10 0 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _